Telomeres, Immunity, and Cardiovascular Health From Oxidative Stress and Cellular Senescence to Exercise and Cardiac Rehabilitation

Telomeres, Immunity, and Cardiovascular Health: From Oxidative Stress and Cellular Senescence to Exercise and Cardiac Rehabilitation offers a detailed look at the relationship that exists between immunity, oxidative stress, cellular ageing and cardiovascular health. The book covers the immune system and adaptive immunity, inflammation in atherosclerosis, oxidative stress and immune response in myocardial infarction. One of the big themes of the book is telomere biology, with special emphasis on telomere shortening, oxidative damage, DNA damage and the relevance of these for cardiovascular ageing, as well as the role of telomeres, telomerase and cellular senescence. It also investigates the mechanisms and functions of p38 MAPK activation in inflammatory response, oxidative stress, cellular senescence and related molecular pathways. The book also links these molecular/cellular mechanisms to exercise and cardiac rehabilitation, underscoring their importance for cardiovascular function, inflammation, immune regulation and healthy ageing. It is designed to be a handy resource for students, researchers, academics and health care professionals interested in gaining a wider perspective on the connection between the telomere, immunity, oxidative stress and cardiovascular health.